Interestingly, even though cannabis and nicotine are commonly used together, and have synergistic effects, trials have revealed that CBD may be an effective medication in assisting patients quit using nicotine 11. This echoes the research that CBD may also be effective in limiting the anxiety and other symptoms of withdraw in heroin addicts 12. No conclusions can be drawn yet, as research still needs time to develop, but the ultimately thing to understand that there is research which shows using nicotine and cannabis in tandem does produce a radically different effect on the brain chemistry than using either substance alone. Rejoice spliff and blunt smokers, it could be more than a preference or an addiction to nicotine.